The WAKE UP component promotes opioid and sedation management with the goal of reducing unnecessary sleepiness and sedation, which allows for early mobilization, reduction of delirium, decreased risk of respiratory compromise and shortened length of stay. The interrelated strategy of SCRIPT UP promotes optimizing inpatient medications. Monitoring reversal agents and maintaining a continued emphasis on minimal sedation can assist in the prevention of several harm events: adverse drug events (ADE), airway safety, delirium, failure to rescue, falls, ventilator-associated events (VAE) and venous thromboembolism (VTE).
FHA will focus on WAKE UP April - June 2018.
The acronym is a reminder of the practices an organization needs to have in place to effectively initiate appropriate sedation management:
W - WARN yourself: this is high risk.
A - ASSESS: use tools (STOP-BANG, POSS, RASS, PA-PSA).
K - KNOW: your drugs, your patient.
E - ENGAGE: patients and families to set realistic pain expectations, use of non-sedating analgesics, risks of opioids.
U - UTILIZE: dose limits, layering limits, soft and hard stops.
P - PROTECT: the Patient…our ultimate job.
FHA WAKE UP Newsletters
Health Resource & Educational Trust (HRET)
- Topic-specific resources such as change packages, checklists, guidelines, case studies, peer-shared resources and more are available on the HRET-HIIN.org Web site:
Other Resource Materials
- The Pain Assessment and Management Initiative (PAMI) & The Joint Commission Pain Standards
- Mayo Clinic Non-pharmacological Interventions
- Hospital Elder Life Program (HELP) for Prevention of Delirium
- Sedation, Delirium and Mobility in ICU Patients (Institute for Healthcare Improvement)
- Statement on Preventing Harm from Oversedation in Adult Hospitalized Patients (Oregon Patient Safety Commission)
- Practice Guidelines for Sedation and Analgesia by Non-Anesthesiologists (The Journal of the American Society of Anesthesiologist, Inc., Anesthesiology 4 2002, Vol.96, 1004-1017.)
- Nurses' Role in Improving the Pain Management Culture (IndustryEdge, A Press Ganey Publication, Aug. 2016.)
- Assessment of Sedation during Opioid Administration for Pain Management (Journal of PeriAnesthesia Nursing, Vol 24, No 3 (June), 2009.)
Education and Training for Health Care Providers
For more information, contact FHA MTC HIIN at email@example.com or 407-841-6230.